Evaluating Liver Fibrosis by Transient Elastometry in Patients With HIV-HCV Coinfection and Monoinfection

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Evaluating Liver Fibrosis by Transient Elastometry in Patients With HIV-HCV Coinfection and Monoinfection

BACKGROUND Due to the high efficacy of combination antiretroviral therapy (cART), the number of patients living with HIV is increasing. Chronic HCV infection has become a leading cause of non-AIDS related morbidity and mortality in patients with HIV infection. OBJECTIVES The aim of this cross-sectional study was to identify factors associated with liver fibrosis (LF) in patients with HIV mono...

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evaluating liver fibrosis by transient elastometry in patients with hiv-hcv coinfection and monoinfection

conclusions hcv coinfection, older age and ast were associated with lf in patients with hiv infection. objectives the aim of this cross-sectional study was to identify factors associated with liver fibrosis (lf) in patients with hiv monoinfection and hiv-hcv coinfection. patients and methods we analyzed lf by transient elastometry ([te], fibroscan) in three groups of patients (hiv, hiv-hcv and ...

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The use of transient elastometry for assessing liver fibrosis in patients with HIV and hepatitis C virus coinfection.

BACKGROUND Transient elastometry (TE) is accurate for detecting significant liver fibrosis and cirrhosis in hepatitis C virus (HCV)-monoinfected patients. However, this procedure has been insufficiently validated in patients with human immunodeficiency virus (HIV) and HCV coinfection. The purpose of this study was to validate reported cutoff values of TE that discriminate significant liver fibr...

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Molecular Mechanisms of Liver Fibrosis in HIV/HCV Coinfection

Chronic hepatitis C virus (HCV) infection is an important cause of morbidity and mortality in people coinfected with human immunodeficiency virus (HIV). Several studies have shown that HIV infection promotes accelerated HCV hepatic fibrosis progression, even with HIV replication under full antiretroviral control. The pathogenesis of accelerated hepatic fibrosis among HIV/HCV coinfected individu...

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Predictors of liver fibrosis in HIV-infected patients with chronic hepatitis C virus (HCV) infection: assessment using transient elastometry and the role of HCV genotype 3.

BACKGROUND Liver fibrosis is accelerated in patients coinfected with hepatitis C virus (HCV) and human immunodeficiency virus (HIV). The reasons for this faster liver disease progression are unclear, although higher plasma HCV RNA levels and distinct HCV genotype distribution in this population, compared with in HCV-monoinfected subjects, could play a role. METHODS Liver fibrosis was assessed...

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ژورنال

عنوان ژورنال: Hepatitis Monthly

سال: 2014

ISSN: 1735-143X,1735-3408

DOI: 10.5812/hepatmon.15426